Cinobufotalin reduces glioblastoma resistance to temozolomide by inhibiting the CCL5-mediated PI3K/Akt/mTOR signaling pathway
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Background: Temozolomide (TMZ) resistance is a key factor that restricts the therapeutic effects of glioblastoma (GBM). The pharmacological properties of cinobufotalin (CB) indicated that CB promotes the cell death of GBM cells, ... ...