RNAscope-based HER2 mRNA detection shows high concordance with fluorescence in situ hybridization in invasive breast carcinoma: a retrospective study
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Background: Human epidermal growth factor receptor 2 (HER2) status is critical for guiding targeted therapy in invasive breast cancer (BC). Immunohistochemistry (IHC) is routinely used for HER2 screening, but equivocal (IHC 2+) c... ...