TGF-β-induced Tregs release extracellular vesicles that modulate CD4+ T-cell proliferation and phenotype in a Nrp1-dependent manner
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Neuropilin-1 (Nrp1) is one of the receptors for TGF-β and is associated with the suppressive function of T regulatory cells (Tregs). Based on previous findings on natural Tregs, this work investigated the role of Nrp1 on induced Tregs (iTregs) and their small... ...