SHIP-1 adapter functions mediate recruitment of FCRL1 to the BCR and inhibition of ERK
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FCRL1 is a plasma membrane coreceptor on B cells that has been shown to potentiate B cell receptor (BCR)-driven calcium flux and negatively regulate ERK phosphorylation in a GRB2 and tyrosine-dependent manner. Of the proteins that associate with FCRL1, the rec... ...
