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"EPAC1: Molecular architecture, physiological regulation, and therapeutic implications in diseases"

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Exchange Protein Directly Activated by cAMP 1 (EPAC1) is an intracellular effector of the small GTPases Rap1 and Rap2, functioning independently of protein kinase A in the cAMP signalling pathway. The structural analysis shows that EPAC1 has an N-terminal regu... ...