Emapalumab's role in a severe and treatment-resistant paediatric macrophage activation syndrome
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Introduction Macrophage activation syndrome (MAS) is a life-threatening hyperinflammatory condition. Emapalumab, an IFNγ-directed antibody, is approved for use in the USA but not in Europe. Case A 15-year-old girl presented with fever, odynophagia and a trans... ...