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Antileishmanial activity, cytotoxicity, and immunomodulatory effects of a naphthoquinone derivative

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This study evaluated the antileishmanial activity, toxicity, and immunomodulatory effects of the synthetic compound IM4, derived from β-lapachone. In promastigote forms, IM4 showed IC50 values of 4.82 ± 0.11 μg/mL for L. infantum and 15.76 ± 0.67 μg/mL fo... ...