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A Novel Slowly Self-Emulsifying Drug Delivery System: Prolonged Systemic Exposure of Tacrolimus With Reduced Risks of Systemic Side Effects

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This study aimed to design and characterize a new type of self-emulsifying drug delivery system (SEDDS), slowly SEDDS (SL-SEDDS), for long-lasting systemic exposure of tacrolimus (TAC) with reduced nephrotoxicity. TAC-loaded SL-SEDDS (SL-SEDDS/TAC) was prepare... ...