Molecular insights into the binding of curcumin, γ-oryzanol, and sesamin to cyclooxygenase-2 (COX-2): a computational study
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Cyclooxygenase-2 (COX-2) is a key therapeutic target for inflammatory diseases, cancer, and osteoarthritis (OA). Thus, several COX-2 inhibitors have been developed. However, their clinical use has been limited due to the cardiovascular, hepatic, and renal adve... ...