Design, synthesis and biological evaluation of Chidamide derivatives against breast cancer
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In this study, we designed and synthesized a series of compounds derived from the histone deacetylase inhibitor (HDACi) Chidamide and the BET bromodomain inhibitor (+)-JQ-1. All target compounds were structurally characterized by 1H NMR, 13C NMR, and high-reso... ...