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Understanding thyroid hormone receptor function in controlling developmental timing and rate in Xenopus: A journey from biochemistry and molecular biology to genetics

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Anuran metamorphosis has long been used as a model to study thyroid hormone (T3) function during vertebrate development. The cloning of T3 receptor (TR) in the late 1980 s opened a door for using anuran metamorphosis to address some fundamental questions on T3... ...