Microtubule-stabilizing drugs suppress convulsions in a C. elegans model of CAMSAP disorders
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Recessive, loss of function, genomic variants in CAMSAP1 and 2 (calmodulin-regulated spectrin-associated proteins 1 and 2) cause a neurodevelopmental seizure disorder in humans that currently lacks specific treatments. CAMSAP proteins stabilize dynamics of the... ...
