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Allicin Attenuates Sepsis-Induced Acute Kidney Injury by Inhibiting Pyroptosis Through Negative Regulation of the PI3K/AKT Pathway

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Pyroptosis is a critical mechanism leading to sepsis-induced acute kidney injury (S-AKI). Allicin, an organosulfur compound extracted from garlic bulbs, protects against S-AKI through its anti-pyroptotic role, but the underlying pathophysiological mechanisms r... ...