Fluid shear stress activates c-Src and promotes RANKL localization in the plasma membrane in osteoblast-like MC3T3-E1 cells
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Receptor activator of NF-κB ligand (RANKL) produced by osteoblastic lineage cells is essential for osteoclastogenesis, yet RANKL can be sequestered in intracellular, lysosome-like compartments under basal conditions. How mechanical cues mobilize RANKL toward ... ...
