首页 正文

1H, 13C and 15N resonance assignments of the N-terminal intrinsically disordered region and WGR domain of human PARP2

{{output}}
Poly(ADP-ribose) polymerase 2 (PARP2) is a key sensor of DNA single-strand breaks that catalyzes ADP-ribosylation of itself and other substrates to initiate DNA repair. Human PARP2 contains an intrinsically disordered N-terminal domain (NTD) that mediates chro... ...