Engineered Mesenchymal Stem Cells with Endogenous Trehalose Expression Activate the NRF2-HMOX1 Pathway to Enhance Antioxidant Stress and Wound Healing Capacity
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Objective: Oxidative stress limits mesenchymal stem cell (MSC) efficacy in tissue repair by reducing retention and survival at injury sites. Endogenous production of trehalose may enhance MSC resilience and promote skin wound hea... ...