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Synthesis of Carbon-13 and Carbon-14 Labeled BI 690517 (Vicadrostat) and Its O-Glucuronide Metabolite BI 689875

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Vicadrostat, also known as BI 690517 (1) is a novel, potent, and selective aldosterone synthase CYP11B2 inhibitor being developed in combination with empagliflozin to slow the progression of kidney damage and reduce cardiovascular events in people with chronic... ...