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Identification and credentialing of invasive lobular carcinoma patient-derived Xenograft models

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Invasive lobular cancer (ILC) is the most common special breast cancer subtype, accounting for 10-15% of all cases. The pathognomonic feature of ILC is loss of E-cadherin (CDH1), leading to discohesive single-file growth. Although ILCs show better prognostic f... ...