Intelligent delivery of autophagy-targeting chimeric peptides by engineered exosomes for the degradation of α-synuclein
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Targeted degradation of the aggregated α-synuclein holds tremendous potential for treating Parkinson's disease (PD). However, most of the developed aggregated α-synuclein-specific degraders, e.g., autophagy-targeting chimeric peptides, are limited by the bl... ...