Discovery of spiroindolediketopiperazine alkaloids from Penicillium sp. KYS-32 as dual inhibitors of ABCB1 and ABCG2 to reverse multidrug resistance
{{output}}
Chemical investigation of the fungus Penicillium sp. KYS-32 afforded eleven spiroindolediketopiperazine alkaloids (1-11), including seven previously unreported compounds penispiroketins A-G (1-7). Compounds 2, 3, 6, and 7 are characterized by an oxidation at C... ...
