CYP1-bioactivated 2,4-diaryl-substituted pyridine analogues with remarkable activity in a breast cancer in vitro model
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A series of 2,4-diaylpyridine analogues 8(1-9) was synthesised and evaluated for antiproliferative activity against a panel of human tumour and non-tumour breast cell lines that was characterised for CYP1 A1, A2 and B1 isoforms expression. Diarylpyridine 8 (6)... ...
