Evidence for a Role of Calcium and Vitamin D in the Regulation of Manganese Homeostasis and in the Prevention or Management of Manganese Induced Disease
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SLC30A10 mediates Mn efflux in both intestine and liver, protecting against Mn toxicity. In previous studies we found that Slc30a10 is one of the genes most induced by 1,25(OH)2D3 in mouse intestine and human enteroids. In addition, in Slc30a10 knock out mice ... ...