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Interaction of estrogen and interleukin 6 in the progression of lymphangioleiomyomatosis

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Lymphangioleiomyomatosis (LAM) is an estrogen-dependent disease that promotes tumor cell growth through estrogen receptor α (ERα). Interleukin 6 (IL-6) is an important estrogen (E2) target gene; however, its role in disease progression remains unclear. In th... ...