Single-cell transcriptomics reveal PRRC1 as a malignant cell enriched driver of DNA repair and therapy resistance in glioblastoma
{{output}}
Glioblastoma (GBM) is the most aggressive primary brain tumor and remains largely refractory to radiotherapy and temozolomide-based therapy. Although these treatments induce DNA damage, GBM cells frequently survive by activating DNA damage response (DDR) signa... ...
