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Peroxiredoxin 4 suppresses ferroptosis in esophageal squamous cell carcinoma by activating the phosphoinositide 3-kinase signaling pathway

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Peroxiredoxin 4 (PRDX4) has been found to be upregulated and verified to play protective roles against oxidative stress in various tumors. However, its exact function and underlying molecular mechanisms in esophageal squamous cell carcinoma (ESCC) remain uncle... ...