Structure-Guided Engineering of TIGIT to Modulate Its Interaction With Nectin-4, a Tumour-Specific Antigen for the Development of Therapeutic Strategy
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Nectin and nectin-like proteins are cell adhesion molecules belonging to the immunoglobulin superfamily that also play a crucial role in the process of immune modulation by interacting with immune receptors like TIGIT, DNAM-1, CD96 and PVRIG. Nectin-4 is a tum... ...
