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Computational validation of inhibitors for human phosphatidylinositol 4-phosphate 5-kinase-type 1 α protein implicated in cancer

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The phosphoinositides are a family of phospholipids produced by the action of phosphatidylinositol phosphate kinases (PIPKs) that perform sequential phosphorylation of inositol. One of these lipid kinases, phosphatidylinositol 4-phosphate 5-kinase type 1 α (P... ...