Distinct metabolomic and proteomic signatures in Parkinson's disease patients with REM sleep behavior disorder
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Rapid eye movement sleep behavior disorder (RBD) is the most specific prodromal marker of Parkinson's disease (PD), affecting 40-50% of PD patients. PD with RBD (RBD-PD) represents a clinically aggressive subtype characterized by more severe motor and nonmoto... ...
