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Ultra-Performance Liquid Chromatography-Electrospray Ionization-Ion Trap Tandem Mass Spectrometry for Fragmentation of Cyclic Dipeptides: Methodology and Application to the Chemical Profiling of the Fungus Hormonema dematioides

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Cyclic dipeptides (CDPs), distinguished by a 2,5-diketopiperazine core, exhibit a broad spectrum of biological activities. The (un)targeted discovery of CDPs in complex matrices is therefore of considerable interest, and mass spectrometry (MS) offers unrivalle... ...