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Deletion of Cab39 adaptors results in KS-WNK1 independent accumulation of SPAK in biomolecular condensates

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The sodium-chloride cotransporter (NCC) in the distal convoluted tubule regulates renal sodium reabsorption, potassium homeostasis, and blood pressure. NCC phosphorylation is controlled by extracellular potassium via the WNK-SPAK kinase cascade, proposed to in... ...