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Knockdown of EFEMP1 Promotes Ferroptosis by Inactivating PI3K/AKT to overcome the Resistance of Hepatocellular Carcinoma Cells to Sorafenib

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Background and aims: We found epidermal growth factor-containing fibulin-like extracellular matrix protein 1 (EFEMP1) is up-regulated in liver cancer cells exposed to sorafenib for a long time using a bioinformatic tool. Here, th... ...