Discovery of novel repurposed anthelminthics against Trichinella spiralis and albendazole-resistant nematodes through metabolomics-guided virtual screening
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Trichinella spiralis is a parasitic nematode that causes trichinellosis, leading to weakness, muscle pain, facial edema, and potentially death. Albendazole (ABZ) is the current drug of choice; however, resistance has been increasingly reported, highlighting th... ...