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WDR-5 exhibits H3K4 methylation-independent activity during embryonic development in C. elegans

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Background: Histone H3 lysine 4 methylation (H3K4me) is generally associated with active transcription and bivalent chromatin but can also contribute to repression. In metazoans, H3K4 methylation is catalysed by KMT2 methyltransf... ...