The design, synthesis and evaluation of [18F]ASK1-IN-6 as the first Fuorine-18 positron emission tomography radiotracer for ASK1 neuroimaging
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ASK1 is a key regulator in the molecular mechanisms underlying multiple neurological diseases, where it drives oxidative stress, inflammation, and apoptotic pathways. ASK1 has emerged as a potential therapeutic target in a range of neurodegenerative and neuroi... ...
