SiO2 dust induces the transformation of lung fibroblasts to myofibroblasts by activating the S1P-RhoA-YAP signaling pathway
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Silicosis, a prevalent and severe form of pneumoconiosis, is characterized by silicotic nodule formation and extensive pulmonary fibrosis. Caused by prolonged inhalation of free silica (SiO₂) dust, its pathogenesis involves complex regulatory mechanisms that ... ...