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Ferroptosis-Driven Anticancer Activity of 1,3,4-Oxadiazole-Benzimidazole/Acetamide Hybrids: Design, Synthesis, and Biological Profiling

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A series of 1,3,4-oxadiazole-benzimidazole/acetamide derivatives (7a-r) was designed, synthesized, and evaluated for their anticancer activity. NCI-screening results at 10 µM against the 60 human tumor cell line panel revealed a broad-spectrum of antiprolifer... ...