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Piperacillin-tazobactam resistance in Klebsiella pneumoniae is often associated with IS 26- mediated blaSHV-1 amplification in a widespread Klebsiella-adapted plasmid

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Piperacillin-tazobactam (TZP) resistance in Klebsiella pneumoniae involves diverse mechanisms with unclear prevalence and phenotypic impact. To elucidate these mechanisms, we analyzed K. pneumoniae clinical isolates resistant to TZP but susceptible to cefotaxi... ...