Functional nanoplatforms overcoming immune resistance in skin cancers: Targeted immunomodulation, immunogenic cell death, and metabolic remodeling
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Skin cancers, including melanoma, cutaneous squamous cell carcinoma (cSCC), and Merkel cell carcinoma (MCC), present a fundamental paradox: high tumor immunogenicity coexists with profound immune evasion, driven by oncogenic signaling, an immunosuppressive mic... ...