Design and Biological Evaluation of Novel Biphenyl-Dihydropyrimidinone Derivatives with Selective Anticancer and Non-Genotoxic Profiles
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This study reports the p-toluenesulfonic acid-catalyzed synthesis of three novel 3,4-dihydropyrimidin-2(1H)-one derivatives (4a = PMe, 4b = PPh, 4c = PNO₂) based on a 1,1'-biphenyl, and the evaluation of their cytotoxic, genotoxic, antioxidant, and apoptosis... ...
