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Circulating Platelet-Neutrophil Aggregates as Novel Biomarker for Coagulopathy Diagnosis and Disseminated Intravascular Coagulation Prediction in Sepsis

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Background: Platelet-leukocyte aggregates (PLAs) drive immunothrombosis by promoting leukocyte activation and tissue factor release in sepsis. However, their utility as early predictors of sepsis-induced coagulopathy (SIC) and di... ...