The IDO1/AhR-HIF-1α metabolic axis: ARNT competition as a central antagonistic switch in autoimmune pathogenesis
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The immunometabolic checkpoint axis formed by the IDO1/AhR pathway and the HIF-1α pathway, which functionally antagonize each other via their competition for the shared transcriptional partner aryl hydrocarbon receptor nuclear translocator (ARNT), profoundly ... ...