Photocatalytic Difluoromethylation Cyclization and Dioxygen Trapping: Access to gem-Difluoro-Quinolines
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Herein, a novel photocatalytic 6-exo-trig difluoromethylation cyclization and subsquent domino O2 trap version is described. This protocol allows efficient access to structurally diverse 4-(hydroxymethyl)-gem-difluoro-quinolines under mild conditions. Broad su... ...
