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IPMK-1 governs C. elegans physiology through ceTOR but lifespan via a distinct IP3-dependent pathway

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Inositol-polyphosphate multikinase (IPMK) is a pleiotropic enzyme essential for metabolic homeostasis, cancer, neural function, and development. While mammalian IPMK is well-characterized, the systemic integration of its signaling outputs - ranging from metabo... ...