Persistence and Fab-Specific Interaction of Acyl-Protein Thioestere-1 with Monoclonal Antibodies During Downstream Processing
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Difficult-to-remove host cell proteins (HCPs) can compromise monoclonal antibody (mAb) product quality and stability. This study investigated the persistence of acyl-protein thioesterase-1, a polysorbate-degrading HCP, during downstream processing and its inte... ...
