Design, synthesis and biological evaluation of novel 3,4-dihydro-2(1 H)-quinoline- O-carbamate derivatives as AChE/MAO-B dual inhibitors for the treatment of Alzheimer's disease
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Alzheimer's disease (AD) is an irreversible degenerative disorder of the brain, and there is no effective drug for it to date. Given its complex pathogenesis, the multi-target-directed ligand (MTDL) strategy is considered as a promising approach against AD. H... ...
