Oral Delivery of siSIRPα via Yeast-Derived β-Glucan Particles Enhances Macrophage-Mediated Antitumor Immunity by Blocking the CD47-SIRPα Axis
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Introduction: The CD47-SIRPα Axis functions as a key innate immune checkpoint that enables tumors to evade phagocytosis and immune surveillance. Blockade of this interaction has emerged as a promising anticancer immunotherapy st... ...
