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Forced degradation analysis of recombinant adeno-associated virus serotype 8 based on analytical anion exchange chromatography coupled to orthogonal characterization

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As a leading vector for gene therapy, recombinant adeno-associated virus (rAAV) has been widely investigated and used. Forced degradation analysis is required to understand the molecular properties and stability of rAAV. In this study, we have applied an analy... ...