Cerebrospinal fluid D-2-hydroxyglutarate for IDH-mutant glioma monitoring
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Background: Imaging-based glioma monitoring is confounded by treatment-related changes. D-2-hydroxyglutarate (D-2-HG), produced by the isocitrate dehydrogenase (IDH) mutation, is detectable in cerebrospinal fluid (CSF), which can... ...
