Relationships Between Polygenic Scores for Psychopathology and Observed Psychopathology Are Mediated by Cognitive Control and Reward Sensitivity Pathways: Insights From the ABCD Study
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Background: Psychiatric disorders affect approximately 20% of adolescents in the United States and are both heritable and highly polygenic. Polygenic scores (PGSs) aggregate genetic risk across the genome and in doing so potentia... ...
