1,25-Dihydroxyvitamin D3 attenuates TGF-β1-induced airway remodeling in asthma by inhibiting IL-33 mediated by the ERK1/2 signaling pathway
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Airway remodeling is a central pathological feature of asthma, while 1,25-dihydroxyvitamin D₃ (1,25(OH)₂D₃) has known immunomodulatory and anti-fibrotic properties. And transforming growth factor-β1 (TGF-β1) plays a core role in inducing airway epithelial... ...
